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The Effects of Pilocarpine in Patients with Orofacial Movement Disorder

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¼Ò¼Ó »ó¼¼Á¤º¸
Á¤¼ö¹Î ( Jeong Su-Min ) - ºÎ»ê´ëÇб³ Ä¡ÀÇÇÐÀü¹®´ëÇпø ±¸°­³»°úÇб³½Ç
¿Á¼ö¹Î ( Ok Soo-Min ) - ºÎ»ê´ëÇб³ Ä¡ÀÇÇÐÀü¹®´ëÇпø ±¸°­³»°úÇб³½Ç
ÇãÁØ¿µ ( Heo Jun-Young ) - ºÎ»ê´ëÇб³ Ä¡ÀÇÇÐÀü¹®´ëÇпø ±¸°­³»°úÇб³½Ç
°í¸í¿¬ ( Ko Myung-Yun ) - ºÎ»ê´ëÇб³ Ä¡ÀÇÇÐÀü¹®´ëÇпø ±¸°­³»°úÇб³½Ç
¾È¿ë¿ì ( Ahn Yong-Woo ) - ºÎ»ê´ëÇб³ Ä¡ÀÇÇÐÀü¹®´ëÇпø ±¸°­³»°úÇб³½Ç

Abstract

ÇÏ¾Ç ¹× ±¸°­ÁÖÀ§±ÙÀ°ÀÇ Á¶ÀýµÇÁö ¾Ê´Â ¿òÁ÷ÀÓÀ¸·Î Á¤ÀÇ µÇ´Â ±¸°­¾È¸é¿îµ¿Àå¾Ö(orofacial movement disorder, OMD)´Â ³ëÀÎÃþ¿¡¼­ ¸¹ÀÌ ¹ß»ýÇÏ¸ç ±× ¿øÀÎÀÌ ¾ÆÁ÷ Á¤È®È÷ ¹àÇôÁöÁö ¾Ê°í Ä¡·á¹æ¹ý ¶ÇÇÑ ´Ù¾çÇÏ´Ù. ÀÓ»óÀû Ư¡À» ºÐ¼®ÇÏ°í Ä¡·á¹æ¹ýÀ» ¿¬±¸ÇÑ ÀÚ·á´Â ¸¹ÀÌ ÀÖÀ¸³ª Ÿ¾×ºÐºñ¿Í OMDÀÇ »ó°ü°ü°è¿¡ ´ëÇÑ ±¸Ã¼ÀûÀÎ ¿¬±¸´Â ¾ÆÁ÷ ¾ø´Ù. º» ¿¬±¸¿¡¼­´Â ºÎ»ê´ëÇб³Ä¡°úº´¿ø ±¸°­³»°ú¿¡ ³»¿øÇÑ OMD ȯÀÚ Áß ±¸°­°ÇÁ¶°¨À» È£¼ÒÇÑ 4¸íÀÇ È¯ÀÚ¸¦ Áõ·Ê·Î ÇÏ¿© ÇÊ·ÎÄ«ÇÉ(pilocarpine)À» °æ±¸·Î Åõ¿©ÇÑ ÈÄ OMD Áõ»óÀÇ º¯È­¸¦ °üÂûÇÏ¿´´Ù. ¿¬±¸°á°ú Ÿ¾×ºÐºñ·®ÀÇ ÀúÇϸ¦ º¸¿© ±¸°­°ÇÁ¶ÁõÀ¸·Î Áø´ÜµÈ Áõ·Ê¿Í Á¤»óŸ¾×ºÐºñ·®À» º¸ÀÌ´Â Áõ·Ê ¸ðµÎ¿¡¼­ ÇÊ·ÎÄ«ÇÉÀÇ °æ±¸Åõ¿© ÈÄ OMDÁõ»óÀÇ °³¼±À» º¸¿´´Ù. µû¶ó¼­ ÇâÈÄ OMD¿Í ±¸°­°ÇÁ¶ÁõÀÇ »ó°ü°ü°è¿¡ ´ëÇÑ Ãß°¡ÀûÀÎ ¿¬±¸°¡ ÇÊ¿äÇÒ °ÍÀ¸·Î »ç·áµÈ´Ù.

Orofacial movement disorders (OMD) are uncontrolled movement of the muscles involving the face, tongue, lip and mandible. Due to variable oral and lingual muscles affected, the patients with OMD are interfered with the appropriate performance such as chewing, swallowing and talking. In this study, there are 4 OMD cases with oral dryness that saliva flow rate is decreased or not. The symptoms are improved after oral administration of pilocarpine to 4 patients with OMD. Therefore, we suggest that objective or subjective oral dryness could be etiologic factor in OMD and pilocarpine could be regarded as medication for OMD.

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±¸°­¾È¸é¿îµ¿Àå¾Ö; ±¸°­°ÇÁ¶Áõ; ÇÊ·ÎÄ«ÇÉ
Oral dryness; Orofacial movement disorder; Pilocarpine

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